This article applies as of PRTG 26
PRTG on Linux
It is currently not possible to install a PRTG core server on Linux/Unix systems. In order to run a PRTG core server you need a Windows machine.
Additionally, we recommend that you run PRTG on real hardware (especially when using more than 5,000 sensors). If you must run PRTG on a virtual machine, please have a look here for configuration and fine-tuning recommendations.
Alternatives
If you only have Linux systems, you can use PRTG Hosted Monitor, our hosted PRTG instance, in conjunction with multi-platform probes.
The multi-platform probe is a remote probe that functions on various non-Windows systems. For more information, see the Multi-Platform Probe for PRTG manual.
For more information on how to use the multi-platform probe with PRTG Hosted Monitor, see the Knowledge Base: How do I set up a multi-platform probe with my PRTG Hosted Monitor instance?